Roseomics: a blank slate

Roseomics: a blank slate.

Recent technological advances have led to an explosion in the system-wide profiling of biological processes in the study of herpesvirus biology, herein referred to as '-omics'. In many cases these approaches have revealed novel virus-induced changes to host cell biology that can be targeted with new antiviral therapeutics. Despite these successes, -omics approaches are not widely applied in the...

The Blank Slate: The Modern Denial of Human Nature

The dominant theory of human nature in modern intellectual life is based on the doctrines of the blank slate, the noble savage, and the ghost in the machine; these doctrines are being challenged by the sciences of the mind, brain, genes, and evolution. Behavioral geneticists have found that all behavioral traits are partially heritable—challenging the doctrine of the blank slate. Evolutionary p...

A blank slate? Layer-by-layer deposition of hyaluronic acid and chitosan onto various surfaces.

Although poly(alpha-hydroxy esters), especially the PLGA family of lactic acid/glycolic acid copolymers, have many properties which make them promising materials for tissue engineering, the inherent chemistry of surfaces made from these particular polymers is problematic. In vivo, they promote a strong foreign-body response as a result of nonspecific adsorption and denaturation of serum protein...

Optimizing Slate Recommendations via Slate-CVAE

The slate recommendation problem aims to find the “optimal” ordering of a subset of documents to be presented on a surface that we call “slate”. The definition of “optimal” changes depending on the underlying applications but a typical goal is to maximize user engagement with the slate. Solving this problem at scale is hard due to the combinatorial explosion of documents to show and their displ...

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